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RO7567132

CAT: 0931-T9901A-748-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9901A-748-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
TNF
Related Pathways
Apoptosis
Bioactivity
RO7567132 (FAP-LTBR) is a novel bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, thereby limiting the activation of LTBR to the tumor microenvironment, inducing the formation of local tertiary lymphoid structures (TLS), and reducing systemic toxicity. Its mouse alternative can inhibit breast cancer growth, and the effect is better when combined with atezolizumab. In the mouse colorectal cancer model, it can also enhance immune cell infiltration and TLS-like structure formation.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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CatalogName
GTR18679085-01RO7567132 Antibody

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