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Sigvotatug

CAT: 0931-T9901A-506-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9901A-506-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2764774-90-3
Target
Antibody-Drug Conjugates (ADCs), Integrin
Related Pathways
Antibody-drug Conjugate/ADC Related, Cytoskeletal Signaling
Purity
0.987
Bioactivity
Sigvotatug Vedotin is an antibody-drug conjugate (ADC) designed to selectively target integrin αvβ6-positive tumor cells through an engineered antibody with high specificity. Sigvotatug Vedotin employs a protease-cleavable linker that delivers the cytotoxic payload monomethyl auristatin E (MMAE), a microtubule inhibitor, directly into tumor cells. Upon internalization, MMAE disrupts microtubule organization, inhibits proper cell division, and ultimately results in tumor cell death, providing a targeted strategy in oncology research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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