Products for Research Use Only

REGN7999

CAT: 0931-T9901A-1925-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9901A-1925-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Serine Protease
Related Pathways
Proteases/Proteasome
Bioactivity
REGN7999 is a monoclonal antibody that inhibits TMPRSS6. By suppressing TMPRSS6 activity, REGN7999 prevents HJV cleavage, enhancing BMP6-HJV signaling and increasing serum hepcidin levels. This inhibition aids in alleviating iron overload and impaired erythropoiesis in β-thalassemia mouse models. REGN7999 is applicable for research in β-thalassemia.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C