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IGN523

CAT: 0931-T9901A-1914-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9901A-1914-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Apoptosis, Caspase
Related Pathways
Proteases/Proteasome, Apoptosis
Bioactivity
IGN523 is an anti-CD98 antibody (hCD98, KD = 0.55 nM) that induces antibody-dependent cell-mediated cytotoxicity (ADCC) . It permeabilizes lysosomal membranes and inhibits essential amino acid transport function, leading to caspase-3 and caspase-7 mediated apoptosis of tumor cells. IGN523 inhibits tumor growth in various tumor xenograft models and can be used for research on cancers such as non-small cell lung cancer (NSCLC) and acute myeloid leukemia (AML) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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PTX25683Anti-Human CD98/SLC3A2 (IGN523)
A135941Anti-CD98/SLC3A2 (IGN523) Biosimilar (Monoclonal, IgG)
NBP3-28167CL1Human Monoclonal CD98 Antibody (Ign523) [CoraFluor 1]
MBS1580158-01Research Grade Anti-Human CD98/SLC3A2 (IGN523)

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