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SAR228810

CAT: 0931-T9901A-1849-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9901A-1849-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Beta Amyloid
Related Pathways
Neuroscience
Bioactivity
SAR228810 is a humanized IgG4 monoclonal antibody inhibitor targeting amyloid beta (Aβ), with a dissociation constant (KD) of 0.43 nM for fibrillar Aβ, which is higher than for monomeric Aβ. It significantly hinders brain amyloid plaque formation, oligomer-induced synaptic dysfunction, and neuronal loss. Furthermore, SAR228810 offers substantial protection against Aβ-mediated neurotoxicity. MINT1526A is applicable in Alzheimer's disease imaging and immunotherapy research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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