HB-0017

• Target :

  Interleukin

• Related Pathways :

  Immunology/Inflammation

• Bioactivity :

  HB-0017 is a humanized IgG1? monoclonal antibody inhibitor that targets IL-17A. It effectively blocks IL-17A-induced IL-6 secretion with an IC50 of 2.09 nM. In psoriatic-like mouse models induced by Imiquimod, HB-0017 significantly reduces auricular thickness and alleviates inflammation in arthritis and air pouch mouse models caused by IL-17A. For isotype control, refer to Human IgG1 kappa, Isotype Control.

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2790610-50-1