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HB-0017

CAT: 0931-T9901A-1807-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9901A-1807-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2790610-50-1
Target
Interleukin
Related Pathways
Immunology/Inflammation
Bioactivity
HB-0017 is a humanized IgG1κ monoclonal antibody inhibitor that targets IL-17A. It effectively blocks IL-17A-induced IL-6 secretion with an IC50 of 2.09 nM. In psoriatic-like mouse models induced by Imiquimod, HB-0017 significantly reduces auricular thickness and alleviates inflammation in arthritis and air pouch mouse models caused by IL-17A. For isotype control, refer to Human IgG1 kappa, Isotype Control.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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