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1D09C3

CAT: 0931-T9901A-1797-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9901A-1797-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
791073-97-7
Target
ROS, Apoptosis, JNK, MHC
Related Pathways
Immunology/Inflammation, Apoptosis, MAPK
Bioactivity
1D09C3 is a fully humanized anti-HLA-DR monoclonal antibody. It induces cell apoptosis (apoptosis) and death through a cascade of reactions, including reactive oxygen species (ROS) production, JNK activation, mitochondrial membrane depolarization, and the release of AIF from mitochondria. In xenograft models with JVM-2 cells and GRANTA-519 cells in mice, 1D09C3 demonstrated significant antitumor activity, improving overall survival and median survival time. This compound is applicable in cancer research, including studies on chronic lymphocytic leukemia (CLL) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-P9915901D09C3
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