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HuGAL-FR21

CAT: 0931-T9901A-1749-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9901A-1749-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
FGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
HuGAL-FR21 is a humanized monoclonal IgG1 antibody targeting FGFR2IIIb. It effectively blocks the binding of FGF2, FGF7, and FGF10 to FGFR2IIIb and inhibits FGF-induced phosphorylation of FGFR2IIIb. Additionally, HuGAL-FR21 reduces FGFR2 expression in SNU-16 cells and demonstrates significant antitumor activity in gastric cancer xenograft models in nude mice. This compound is valuable for research in cancers such as gastric cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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T25440-01FR20

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