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KD6001

CAT: 0931-T9901A-1747-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9901A-1747-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2983061-18-1
Target
Others
Related Pathways
Others
Bioactivity
KD6001 is a humanized IgG1κ monoclonal antibody targeting CTLA4. It effectively disrupts the interaction between CTLA-4 and CD80 (IC50: 16 ng/mL) as well as CD86. KD6001 enhances the expression of IL-2 and IFNγ in PHA-activated human lymphocytes, demonstrating potent antitumor activity. It significantly inhibits tumor growth in mouse models with MC38, B16, and Hepa1-6 tumors. KD6001 is applicable in cancer research, including studies on advanced melanoma, hepatocellular carcinoma, and liver cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-P991566KD6001

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