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MT204

CAT: 0931-T9901A-1661-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9901A-1661-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Interleukin
Related Pathways
Immunology/Inflammation
Bioactivity
MT204 is a humanized IgG1 antibody inhibitor that targets IL-2 from human and rhesus monkey sources. It prevents soluble IL-2 from binding to the intermediate-affinity IL-2 receptor and blocks IL-2 bound to CD25 from interacting with the high-affinity IL-2 receptor. In rhesus monkey allogeneic skin transplant models, MT204 shows excellent tolerability and potent immunosuppressive activity. With linear pharmacokinetics, a reasonable serum half-life, and signs of good safety and efficacy, MT204 holds promise for use in immunotherapy.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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