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VGL101

CAT: 0931-T9901A-1026-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9901A-1026-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Others, Apoptosis
Related Pathways
Apoptosis, Others
Bioactivity
VGL101 is a human IgG1 monoclonal antibody (mAb) that targets TREM-2. It acts as a pSYK agonist with an EC50 of 0.77 nM. Under ALSP pathological conditions, VGL101 enhances the survival of microglia and monocyte-derived macrophages, inhibits apoptosis, and aids in restoring cell morphology to resemble the normal activated CSF1R state. It is applicable in leukoencephalopathy research. Recommended isotype control: Human IgG1 kappa, Isotype Control.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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