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Emirodatamab

CAT: 0931-T9901A-098-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9901A-098-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2449199-61-3
Target
FLT
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
Emirodatamab (AMG-427) is an anti-FLT3/CD3 bispecific T-cell engager with an extended half-life. It can induce high cytotoxicity in primary AML progenitor cells and enhance FLT-3 expression. Combining Emirodatamab with anti-PD-1 antibodies increases T-cell dependent cytotoxicity (TDCC) . This compound is under investigation for use in relapsed or refractory AML.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C