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A-1248767

CAT: 0931-T89918-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89918-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2228052-38-6
Target
Bcl-2 Family, Apoptosis
Related Pathways
Apoptosis
Bioactivity
A-1248767, a derivative of A-1210477, is an MCL-1 inhibitor (IC50=23.9 nM; Ki=0.41 nM) known for its anticancer properties. It binds to MCL-1 with high affinity, induces an increase in MCL-1 protein levels inside cells, and promotes apoptosis in tumor cells.
Smiles
O=C(O)C1=C(C=2C=CC=C(C=3C(=NN(C3C)C)COC4=CC=C(C=C4)N5CCN(C(=O)N(C)C)CC5)C2N1CCN6CCOCC6)CCCOC7=CC=CC=8C=CC=CC78
Molecular Formula
C47H55N7O6
Molecular Weight
813.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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GTR19237545-01A-1248767

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