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(-) BI97D6

CAT: 0931-T89441-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89441-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1430067-36-9
Bioactivity
(-) BI97D6 is a broad-spectrum inhibitor of the Bcl-2 protein family, exhibiting inhibitory effects on Mcl-1, Bcl-2, Bcl-xL, and Bcl-w, with IC50 values of 0.025, 0.031, 0.076, and 0.122 μM respectively. This compound stimulates cell death through the mitochondrial apoptosis pathway mediated by Bak and Bax. Additionally, (-) BI97D6s inhibition of Mcl-1 effectively induces apoptosis in acute myeloid leukemia (AML) cells.
Smiles
O=C1C2=CC(O)=C(O)C(=C2C(=O)C(=C1C=3C(=O)C4=CC(O)=C(O)C(=C4C(=O)C3C)CC=5C=CC=CC5)C)CC=6C=CC=CC6
Molecular Formula
C36H26O8
Molecular Weight
586.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
M11053(-) BI97D6

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