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KHK-6

CAT: 0931-T89399-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89399-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
MAPK
Related Pathways
MAPK
Bioactivity
KHK-6 is an inhibitor of serine/threonine kinase hematopoietic progenitor kinase 1 (HPK 1), with an IC50 of 20 nM. This compound enhances cytokine production induced by CD3/CD28 and upregulates the expression of CD69, CD25, and HLA-DR markers on CD4+ and CD8+ T cells. Additionally, KHK-6 augments the T cell-mediated cytotoxicity against SKOV3 and A549 cells.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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