Products for Research Use Only

UNC10245380

CAT: 0931-T89144-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89144-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
TNF, Akt, ERK
Related Pathways
PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Apoptosis, MAPK
Bioactivity
UNC10245380 is a CIB1 inhibitor with an IC50 of 8 μM. It also inhibits the phosphorylation of AKT and ERK while upregulating the expression of TRAIL-R1/D5. UNC10245380 specifically kills cancer cells that are dependent on CIB1, demonstrating its potential value in the development of CIB1 probes and cancer research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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