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K284-6111

CAT: 0931-T88963-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T88963-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
702668-62-0
Bioactivity
K284-6111 is an orally effective inhibitor of the Chitinase 3-like 1 protein (CHI3L1) . It functions by reducing the expression of inflammatory proteins such as iNOS, COX-2, GFAP, and Iba-1, and inhibits both β-secretase (β-secretase) and NF-κB, leading to a suppression of Aβ production. Furthermore, K284-6111 improves memory impairment in mice induced by Aβ1–42, making it useful for research in Alzheimers disease.
Smiles
O=C1C=2C=C(OC)C(OC)=CC2N=C(SC(C(=O)NC3=CC=C(C=C3)CC)CC)N1CCC4=CCCCC4
Molecular Formula
C30H37N3O4S
Molecular Weight
535.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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