Products for Research Use Only

SP3N

CAT: 0931-T88869-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T88869-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
FKBP, Ligands for Target Protein for PROTAC
Related Pathways
PROTAC, Immunology/Inflammation, Autophagy, Apoptosis
Bioactivity
SP3N acts as a specific degrader of the prolyl isomerase FKBP12, converting through amine oxidase metabolism into the active aldehyde precursor (SP3CHO) . This compound subsequently recruits the SCFFBXO22 E3 ligase to mediate the degradation of FKBP12. SP3N is employed in research for cancer therapy.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C