Sp-2-Cl-cAMPS

CAT: 0931-T88786-01Size: 100 mgDry Ice: NoHazardous: No

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CAT#:0931-T88786-01Size:100 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

124854-63-3

Target

Parasite, PKA

Related Pathways

Tyrosine Kinase/Adaptors, Microbiology/Virology

Bioactivity

Sp-2-Cl-cAMPS serves as an agonist for PKA, boasting enhanced membrane permeability and stability against phosphodiesterases. This compound exhibits antimalarial activity, inhibiting the proliferation of the malaria parasite Plasmodium falciparum with an EC50 of 4 μM. Furthermore, Sp-2-Cl-cAMPS binds to the purified regulatory subunit of PfPKA (PfPKAr) with a Ki of 1.3 μM.

Smiles

NC1=C2C(N(C=N2)[C@H]3[C@H](O)[C@]4([C@](O3)(COP(=O)(S)O4)[H])[H])=NC(Cl)=N1

Molecular Formula

C10H11ClN5O5PS

Molecular Weight

379.72

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
HY-137646	Sp-2-Cl-cAMPS
BLG-C004-05	Sp-8-Cl-cAMPS
BLG-C073-05	Rp-2-Cl-cAMPS
TRC-S683608-100MG	Sp-cAMPS
MBS256050-01	2- Chloroadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer (Sp-2-Cl-cAMPS)
BLG-A093-05	Sp-2-AEA-cAMPS
BLG-A024-25	Sp-2′,3′-cAMPS
BLG-A066-25	Sp-2′-AHC-cAMPS
BLG-A095-25	Sp-2′-AEC-cAMPS
BLG-C003-25	Rp-8-Cl-cAMPS

Sp-2-Cl-cAMPS

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