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Trichodermamide B

CAT: 0931-T88748-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T88748-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
508218-12-0
Target
STAT, Apoptosis
Related Pathways
JAK/STAT signaling, Apoptosis, Stem Cells
Bioactivity
Trichodermamide B is a JAK/STAT3 inhibitor that demonstrates potent antiproliferative activity with an IC50 value of 0.12 μM against HCT116 cells. Furthermore, Trichodermamide B induces cell apoptosis (apoptosis) and exhibits anticancer properties.
Smiles
O(C)C1=C2C(C=C(NC(=O)C=3C[C@@]4(O)[C@@](ON3)([C@H](O)C=C[C@H]4Cl)[H])C(=O)O2)=CC=C1OC
Molecular Formula
C20H19ClN2O8
Molecular Weight
450.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C