6-T-GDP

• Target:

  Ras|||Endogenous Metabolite

• Related Pathways:

  Metabolism|||GPCR/G Protein|||MAPK

• Bioactivity:

  6-T-GDP (6-Thioguanosine 5'-diphosphate) is a metabolite of thiopurine. It inhibits the activity of Rac1, thereby reducing the transcription of inflammatory factors and the expression of cell adhesion molecules, which ultimately suppresses leukocyte migration and the occurrence of tissue inflammation.

• Smiles:

  O[C@H]1[C@H](N2C3=C(N=C2)C(=S)N=C(N)N3)O[C@H](COP(OP(=O)(O)O)(=O)O)[C@H]1O

• Molecular Formula:

  C10H15N5O10P2S

• Molecular Weight:

  459.27

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  16541-19-8