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Sp-8-pCPT-cGMPS

CAT: 0931-T88620-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T88620-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
160385-87-5
Target
PKA
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
Sp-8-pCPT-cGMPS is a potent agonist for cyclic guanosine monophosphate-gated (CNG) channels and serves as a lipophilic activator for PKG (types I α, I β, and II) and PKA II. It exhibits excellent cell membrane permeability and stability against phosphodiesterases. This compound is utilized in studying the role of cGMP in synaptic transmission and neural plasticity.
Smiles
S(C=1N(C2=C(N1)C(=O)N=C(N)N2)[C@H]3[C@H](O)[C@]4([C@](O3)(COP(=O)(S)O4)[H])[H])C5=CC=C(Cl)C=C5
Molecular Formula
C16H15ClN5O6PS2
Molecular Weight
503.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C