Products for Research Use Only
RegisterLogin

Eticlopride

CAT: 0931-T88575-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T88575-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
84226-12-0
Target
Dopamine Receptor
Related Pathways
GPCR/G Protein, Neuroscience
Bioactivity
Eticlopride is a potent and selective D2 receptor antagonist that has been studied in rats with extensive dopamine denervation induced by 6-hydroxydopamine. Administering Eticlopride daily for 21 days increases D2 receptor density in intact brain regions; however, it does not further elevate the already increased density in denervated areas. Despite changes in receptor density, functional sensitivity remains evident, as demonstrated by the contralateral rotations induced by the D2 agonist quinpirole during the washout period. This study suggests that chronic D2 receptor blockade and dopamine denervation may share a common mechanism in upregulating D2 receptor density, contrary to previous reports of additive effects with denervation and antagonist treatment.
Smiles
C(NC[C@H]1N(CC)CCC1)(=O)C2=C(OC)C(Cl)=CC(CC)=C2O
Molecular Formula
C17H25ClN2O3
Molecular Weight
340.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-121129Eticlopride
B6874-25Eticlopride hydrochloride
463400-01R (+) -Eticlopride
HY-103413-01Eticlopride (hydrochloride)
326812Eticlopride HCl
414123Eticlopride Free Base
sc-296183AR (+) -Eticlopride hydrochloride

Popular Products