Rugonersen sodium

• CAS Number :

  2591588-58-6

• Target :

  E1/E2/E3 Enzyme

• Related Pathways :

  Ubiquitination

• Bioactivity :

  Rugonersen sodium is a locked nucleic acid (LNA) -modified antisense oligonucleotide (ASO) designed to reduce the silencing of ubiquitin protein ligase E3A (UBE3A) . Angelman syndrome (AS) refers to a severe neurodevelopmental disorder caused by the loss of neuronal E3 ligase UBE3A, and Rugonersen has been studied for its potential use in the treatment of AS.

• Molecular Formula :

  C204H235N63Na19O109P19S19

• Molecular Weight :

  6948

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C