Products for Research Use Only
RegisterLogin

Retagliptin hydrochloride

CAT: 0931-T88355-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T88355-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1174038-86-8
Target
Proteasome, Glucagon Receptor, Others
Related Pathways
Others, Proteases/Proteasome, GPCR/G Protein, Ubiquitination
Bioactivity
Retagliptin (SP2086) hydrochloride serves as a potent inhibitor of dipeptidyl peptidase-4 (DPP-4) and beta-amino acids. This compound aids in the management of type 2 diabetes and enhances glycemic control by extending the activity of intestinal hormones, notably glucagon-like peptide-1 (GLP-1) .
Smiles
C(OC)(=O)C1=C2N(C(C(F)(F)F)=N1)CCN(C(C[C@@H](CC3=C(F)C=C(F)C(F)=C3)N)=O)C2.Cl
Molecular Formula
C19H19ClF6N4O3
Molecular Weight
500.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Retagliptin hydrochloride
CAS Number1174038-86-8
PubChem CID44193829
IUPAC Namemethyl 7-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(trifluoromethyl)-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxylate;hydrochloride
Molecular FormulaC19H19ClF6N4O3
Molecular Weight500.8
Topological Polar Surface Area90.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count11
Rotatable Bond Count6
Heavy Atom Count33
Formal Charge0
Complexity698
SMILES
COC(=O)C1=C2CN(CCN2C(=N1)C(F)(F)F)C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.Cl
InChI
InChI=1S/C19H18F6N4O3.ClH/c1-32-17(31)16-14-8-28(2-3-29(14)18(27-16)19(23,24)25)15(30)6-10(26)4-9-5-12(21)13(22)7-11(9)20;/h5,7,10H,2-4,6,8,26H2,1H3;1H/t10-;/m1./s1
InChIKey
DIUZSRUIUOLMSO-HNCPQSOCSA-N
Chemical Structure
2D Structure
2D structure of Retagliptin hydrochloride
CAS: 1174038-86-8
CID: 44193829
Formula: C19H19ClF6N4O3
MW: 500.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight500.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count11
Rotatable Bond Count6
Exact Mass500.1049871
Monoisotopic Mass500.1049871
Topological Polar Surface Area90.5 Ų
Heavy Atom Count33
Formal Charge0
Complexity698
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
T28520Retagliptin
T12710-01Retagliptin Phosphate
T77217Saccharopine hydrochloride
T23379-01Solifenacin hydrochloride
T38447-01BN82002 hydrochloride
T40896Bromchlorbuterol hydrochloride
T33939-01Dagrocorat hydrochloride
T36365-01KAPA hydrochloride
T0204Protriptyline hydrochloride
T12877-01Seltorexant hydrochloride

Alternative Products

CatalogName
GTR19233858-01Retagliptin hydrochloride
HY-112668BRetagliptin (hydrochloride)
BA7305-5Retagliptin
HY-112668-01Retagliptin (phosphate)
MBS3613108-01Retagliptin Phosphate
RM-R010103-01Retagliptin Acid
A19777-100Retagliptin Phosphate 100mg
A19777-50Retagliptin Phosphate 50mg
A19777-25Retagliptin Phosphate 25mg
A19777-10Retagliptin Phosphate 10mg

Popular Products