HIF-2α-IN-12

CAT: 0931-T88300-01Size: 100 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T88300-01Size:100 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

3034488-33-7

Target

HIF/HIF Prolyl-Hydroxylase

Related Pathways

Metabolism, Chromatin/Epigenetic

Bioactivity

HIF-2α-IN-12 (9) acts as an inhibitor of HIF-2α, exhibiting an IC 50 value of 0.9 μM.

Smiles

N#CC1=CC(F)=CC(=C1)NC(=S)N2CC(F)(F)C(O)C23CCCC3

Molecular Formula

C16H16F3N3OS

Molecular Weight

355.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Hif-2|A-IN-12

CAS Number	3034488-33-7
PubChem CID	171714330
IUPAC Name	N-(3-cyano-5-fluorophenyl)-3,3-difluoro-4-hydroxy-1-azaspiro[4.4]nonane-1-carbothioamide
Molecular Formula	C16H16F3N3OS
Molecular Weight	355.4
XLogP	2.4
Topological Polar Surface Area	91.4
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	1
Heavy Atom Count	24
Formal Charge	0
Complexity	558

SMILES

C1CCC2(C1)C(C(CN2C(=S)NC3=CC(=CC(=C3)C#N)F)(F)F)O

InChI

InChI=1S/C16H16F3N3OS/c17-11-5-10(8-20)6-12(7-11)21-14(24)22-9-16(18,19)13(23)15(22)3-1-2-4-15/h5-7,13,23H,1-4,9H2,(H,21,24)

InChIKey

GNDGGINSWHHCHE-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 3034488-33-7

CID: 171714330

Formula: C16H16F3N3OS

MW: 355.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	355.4
XLogP3	2.4
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	1
Exact Mass	355.09661780
Monoisotopic Mass	355.09661780
Topological Polar Surface Area	91.4 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	558
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
T11561-01	HIF-2α-IN-2
T88052-01	HIF-2α-IN-13
T61458-01	HIF-PHD-IN-2
T11562-01	HIF-2α-IN-3
T78937-01	HIF-2α-IN-9
T88307-01	HIF-2α-IN-16
T61349-01	HIF-1α-IN-2
T61614-01	HIF-2α-IN-5
T50099-01	HIF-2α-IN-4
T15482-01	HIF-2α-IN-1

Alternative Products

Catalog	Name
GTR19233912-01	HIF-2α-IN-12
PA1129-S	HIF-2α
XRC66682-01	HIF-2α-IN-2
TBI1508-5MG	HIF-2a-I2, HIF-2 antagonist
M32959-01	HIF-2α-IN-3
M28457-01	HIF-2α-IN-4
BA7799-5	HIF-1α-IN-2
HY-19949-01	HIF-2α-IN-1
MBS5804053	HIF-1alpha-IN-2
BUP09166-01	HIF-2a-IN-2

HIF-2α-IN-12

Chemical Information

Related Products

Alternative Products

Popular Products