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DBCO-PEG3 acetic-EVCit-PAB

CAT: 0931-T87762-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T87762-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2253947-17-8
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
DBCO-PEG3 acetic-EVCit-PAB, a cleavable 3-unit PEG ADC linker, plays a crucial role in the synthesis of antibody-drug conjugates (ADCs) [1]. This compound features a DBCO group, enabling it to engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-bearing molecules, and is also utilized as a click chemistry reagent.
Smiles
C(CCC(NCCOCCOCCOCC(N[C@H](C(N[C@H](C(N[C@H](C(NC1=CC=C(CO)C=C1)=O)CCCNC(N)=O)=O)C(C)C)=O)CCC(OC(C)(C)C)=O)=O)=O)(=O)N2C=3C(C#CC=4C(C2)=CC=CC4)=CC=CC3
Molecular Formula
C54H72N8O13
Molecular Weight
1041.2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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