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Z57346765

CAT: 0931-T87659-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T87659-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1016340-64-9
Target
Others, PGK1
Related Pathways
Others, Metabolism
Purity
0.9985
Bioactivity
Z57346765 is a specific PGK1 (Phosphoglycerate kinase 1) inhibitor that inhibits PGK1-dependent cell proliferation by decreasing the metabolic enzyme activity of PGK1 during glycolysis. In the clinical phase, Z57346765 had a dose-dependent inhibitory effect on locally advanced renal clear cell carcinoma (KIRC) by inducing changes in the expression of genes related to cell metabolism, DNA replication, and the cell cycle.
Smiles
OCCNC=1N=C(N=C2C=CC=CC21)NC3=CC=C(C=C3)C
Molecular Formula
C17H18N4O
Molecular Weight
294.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BUP20047-01Z57346765
C04927-1gZ57346765 hydrochloride

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