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UGT1A1-IN-1

CAT: 0931-T87592-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T87592-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2097024-37-6
Target
UGT
Related Pathways
Metabolism
Bioactivity
UGT1A1-IN-1 (compound 2) acts as a non-competitive inhibitor of UGT1A1, effectively inhibiting the 1-O-glucuronidation process mediated by UGT1A1 with a Ki value of 5.02 μM. This compound binds to the same ligand-binding site on UGT1A1 as bilirubin and additionally functions as a 'turn-on' fluorescent probe substrate for UGT1A1 [1].
Smiles
O=C1C=2C3=C(C(=CC2)C4=CC=C(O)C=C4)C=CC=C3C(=O)N1CCCC
Molecular Formula
C22H19NO3
Molecular Weight
345.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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