SE-7552

• CAS Number :

  2243575-79-1

• Target :

  HDAC

• Related Pathways :

  Chromatin/Epigenetic|||DNA Damage/DNA Repair

• Bioactivity :

  SE-7552, a derivative of 2- (difluoromethyl) -1,3,4-oxadiazole (DFMO), serves as an orally active, highly selective non-hydroxamate HDAC6 inhibitor, boasting an IC50 of 33 nM. It exhibits over 850-fold selectivity against all other known HDAC isozymes. Demonstrating efficacy in vivo, SE-7552 effectively inhibits the growth of multiple myeloma. Additionally, it functions as an anti-obesity agent in diet-induced obese mice [1] [2].

• Smiles :

  C(F)(F)C=1OC(=NN1)C=2C=NC(NC(C)C3=CC=C(F)C=C3)=NC2

• Molecular Formula :

  C15H12F3N5O

• Molecular Weight :

  335.28

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C