SE-7552

CAT: 0931-MF-0121327-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0121327-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2243575-79-1
Target
HDAC
Related Pathways
Chromatin/Epigenetic|||DNA Damage/DNA Repair
Bioactivity
SE-7552, a derivative of 2- (difluoromethyl) -1,3,4-oxadiazole (DFMO), serves as an orally active, highly selective non-hydroxamate HDAC6 inhibitor, boasting an IC50 of 33 nM. It exhibits over 850-fold selectivity against all other known HDAC isozymes. Demonstrating efficacy in vivo, SE-7552 effectively inhibits the growth of multiple myeloma. Additionally, it functions as an anti-obesity agent in diet-induced obese mice [1] [2].
Smiles
C(F)(F)C=1OC(=NN1)C=2C=NC(NC(C)C3=CC=C(F)C=C3)=NC2
Molecular Formula
C15H12F3N5O
Molecular Weight
335.28
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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