Products for Research Use Only
RegisterLogin

RNA polymerase-IN-2

CAT: 0931-T87338-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T87338-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2447106-79-6
Target
Others, DNA/RNA Synthesis
Related Pathways
Others, DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Bioactivity
RNA polymerase-IN-2 (compound 5) acts as an inhibitor of DNA-dependent RNA polymerase. Additionally, it inhibits CYP isozymes [1].
Molecular Formula
C47H57N3O14
Molecular Weight
887.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

[(7S,9Z,11S,12R,13S,14R,15R,16R,17S,18S,19Z,21E)-30-[2-(dimethylamino)ethoxy]-2,6,15,17-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-23,32,37-trioxo-8,27,38-trioxa-34-azahexacyclo[23.11.1.14,7.05,36.026,35.028,33]octatriaconta-1,3,5,9,19,21,25,28,30,33,35-undecaen-13-yl] acetate
CAS Number2447106-79-6
PubChem CID177864550
IUPAC Name[(7S,9Z,11S,12R,13S,14R,15R,16R,17S,18S,19Z,21E)-30-[2-(dimethylamino)ethoxy]-2,6,15,17-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-23,32,37-trioxo-8,27,38-trioxa-34-azahexacyclo[23.11.1.14,7.05,36.026,35.028,33]octatriaconta-1,3,5,9,19,21,25,28,30,33,35-undecaen-13-yl] acetate
Molecular FormulaC48H58N2O14
Molecular Weight887.0
XLogP2.4
Topological Polar Surface Area220
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count16
Rotatable Bond Count7
Heavy Atom Count64
Formal Charge0
Complexity2370
SMILES
C[C@H]1/C=C\C=C(\C(=O)CC2=C3C(=C4C(=C(C(=C5C4=C([C@](O5)(O/C=C\[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)O)C)O)C2=O)N=C6C(=CC(=CC6=O)OCCN(C)C)O3)/C
InChI
InChI=1S/C48H58N2O14/c1-22-13-12-14-23(2)40(54)25(4)41(55)26(5)44(62-28(7)51)24(3)33(59-11)15-17-61-48(8)47(58)37-35-36(42(56)27(6)45(37)64-48)43(57)30(21-31(22)52)46-39(35)49-38-32(53)19-29(20-34(38)63-46)60-18-16-50(9)10/h12-15,17,19-20,23-26,33,40-41,44,54-56,58H,16,18,21H2,1-11H3/b14-12-,17-15-,22-13+/t23-,24+,25+,26+,33-,40-,41+,44+,48-/m0/s1
InChIKey
YEFQWNSELYYXDD-OBJBWHGKSA-N
Chemical Structure
2D Structure
2D structure of [(7S,9Z,11S,12R,13S,14R,15R,16R,17S,18S,19Z,21E)-30-[2-(dimethylamino)ethoxy]-2,6,15,17-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-23,32,37-trioxo-8,27,38-trioxa-34-azahexacyclo[23.11.1.14,7.05,36.026,35.028,33]octatriaconta-1,3,5,9,19,21,25,28,30,33,35-undecaen-13-yl] acetate
CAS: 2447106-79-6
CID: 177864550
Formula: C48H58N2O14
MW: 887.0
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight887.0
XLogP32.4
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count16
Rotatable Bond Count7
Exact Mass886.38880453
Monoisotopic Mass886.38880453
Topological Polar Surface Area220 Ų
Heavy Atom Count64
Formal Charge0
Complexity2370
Isotope Atom Count0
Defined Atom Stereocenter Count9
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count3
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T74631-01RNA polymerase II-IN-2
T79923-01T7 RNA polymerase
T212143-01RNA polymerase-IN-3
T87337-01RNA polymerase-IN-1
T74630-01RNA polymerase II-IN-1
TMPY-06071-01SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His)
TMAB-12272-01Anti-RNA polymerase II Polyclonal Antibody
TMAB-12269-01Anti-RNA polymerase beta Antibody (5L900)
T89940-01IN-RNA-IN-2
T79307-01DNA polymerase-IN-2

Alternative Products

CatalogName
HY-155092DNA polymerase-IN-2
HY-163016RNA polymerase-IN-2
GTR19221078-01RNA polymerase II-IN-2
GTR19249993-01HCV NS5B polymerase-IN-2
040248POLL, CT (POLL, DNA polymerase lambda, DNA polymerase beta-2, DNA polymerase kappa)
131567POLE2 (DPE2, DNA Polymerase epsilon Subunit 2, DNA Polymerase II Subunit 2, DNA Polymerase epsilon Subunit B)
330105Poly (ADP-ribose) polymerase 2
MBS8582351-01DNA Polymerase gamma 2 Antibody
NEB M0537SBst 2.0 DNA Polymerase
AP86168-01Poly [ADP-ribose] polymerase 2

Popular Products