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LLK203

CAT: 0931-T86816-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T86816-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2758090-62-7
Target
Apoptosis, DUB
Related Pathways
Cell Cycle/Checkpoint, Ubiquitination, Apoptosis, DNA Damage/DNA Repair
Bioactivity
LLK203 is a potent dual-target inhibitor of USP2/USP8 with IC50 values of 0.89 μM and 0.52 μM, respectively. It promotes ERα degradation and induces apoptosis in breast cancer MCF-7 cells, demonstrating antitumor activity in the 4T1 tumor mice model [1].
Smiles
C(NC1=NC(=CS1)C2=CC=CC=C2)(=O)C3=C(NS(=O)(=O)C4=CC=C(C=C4)C=5SC(C)=CC5)C=C(OC)C=C3
Molecular Formula
C28H23N3O4S3
Molecular Weight
561.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-162312-01LLK203

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