GZ-11608

CAT: 0931-MF-0147614-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0147614-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2141974-01-6
Target
Monoamine Transporter
Related Pathways
Membrane transporter/Ion channel
Bioactivity
GZ-11608, a selective and potent inhibitor of vesicular monoamine transporter-2 (VMAT2), presents a high affinity with a Ki value of 25 nM. It effectively reduces dopamine release induced by methamphetamine from isolated synaptic vesicles in brain dopaminergic neurons. GZ-11608 also demonstrates rapid penetration into the brain without exhibiting neurotoxicity, making it a valuable compound for researching methamphetamine use disorder [1].
Smiles
C([C@@H](NCCCC1=CC=C(OC)C=C1)C)C2=CC=CC=C2
Molecular Formula
C19H25NO
Molecular Weight
283.41
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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