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GW814408X

CAT: 0931-T86538-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T86538-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
886599-05-9
Target
Aurora Kinase, Others
Related Pathways
Chromatin/Epigenetic, Others, Cell Cycle/Checkpoint
Bioactivity
GW814408X, a kinase chemical genome group (KCGS) compound, inhibits the AURKC kinase, which is involved in cell cycle progression, checkpoint regulation, and cell division. It exhibits cell line-dependent toxicity, such as cytotoxic effects on HeLa cells, and acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases, potentially impacting Fluc reporter assays [1].
Smiles
N(N=CC=1C=CN=CC1)C2=C3C(C(=CN3)C4=CC(OC)=CC=C4)=NC=N2
Molecular Formula
C19H16N6O
Molecular Weight
344.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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