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GW694590A

CAT: 0931-T86534-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T86534-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
948313-24-4
Target
PDGFR, c-Kit, c-Myc, Discoidin Domain Receptor (DDR)
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Cell Cycle/Checkpoint
Bioactivity
GW694590A (UNC10112731) functions as a MYC protein stabilizer that enhances the levels of endogenous MYC protein. It also acts on receptor tyrosine kinases, inhibiting DDR2, KIT, and PDGFRα by 81%, 68%, and 67% at a concentration of 1 μM, respectively. As a protein kinase inhibitor, GW694590A affects both ATP-dependent and ATP-independent luciferases, potentially influencing the Fluc reporter gene [1].
Smiles
N(C(OC)=O)C=1NC=2C(N1)=CC=C(OC3=CC=C(NC(NC4=CC=CC=C4)=O)C=C3)C2
Molecular Formula
C22H19N5O4
Molecular Weight
417.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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