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EP3 antagonist 6

CAT: 0931-T86375-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T86375-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
499149-94-9
Target
Prostaglandin Receptor
Related Pathways
Immunology/Inflammation, GPCR/G Protein
Bioactivity
EP3 antagonist 6 (compound 5), a selective and orally active EP3 receptor antagonist, exhibits potent activity with an IC 50 of 1.9 nM. It effectively inhibits PGE2-induced uterine contractions in pregnant rats [1].
Smiles
C(N[C@H](CC(C)C)C1=CC(C)=CC(C)=C1)(=O)C2=C(CCC(O)=O)C=CC(COC3=C(C)C=CC=C3)=C2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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