ALR-27

CAT: 0931-T85637-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T85637-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

903639-13-4

Target

FLAP

Related Pathways

Immunology/Inflammation

Bioactivity

ALR-27 serves as an antagonist of the 5-lipoxygenase (5-LOX) activating protein FLAP and exhibits anti-inflammatory properties. It effectively inhibits 5-LOX product formation (>80%) in pro-inflammatory M1-MDM without significantly inhibiting 5-LOX directly. Additionally, ALR-27 decreases prostaglandin and leukotriene (LT) production in neutrophils and enhances the production of specialized prolytic mediators in certain human macrophage phenotypes [1].

Smiles

C(CC1=CC=C(O)C=C1)C2CCC(CO2)C3=CC=C(O)C=C3

Molecular Formula

C19H22O3

Molecular Weight

298.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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