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1400W

CAT: 0931-T85385-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T85385-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
180001-34-7
Target
Apoptosis|||NO Synthase
Related Pathways
Apoptosis|||Immunology/Inflammation
Bioactivity
1400W is a slow, tight-binding, and highly selective inducible nitric-oxide synthase (iNOS) inhibitor, with a K_d value ? 7 nM. 1400W inhibits iNOS induction in microglial cells and reduces the generation of NO, thereby mitigating oxidative stress and neuronal cell apoptosis in the rat cerebral cortex, and improving spatial memory dysfunction caused by acute hypobaric hypoxia-reoxygenation [1] [2].
Smiles
N=C(NCC=1C=CC=C(C1)CN)C
Molecular Formula
C10H15N3
Molecular Weight
177.25
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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