Monohydroxy Melphalan hydrochloride

• Target:

  Others|||Drug Metabolite

• Related Pathways:

  Metabolism|||Others

• Bioactivity:

  Monohydroxy melphalan, a degradation product and DNA alkylating agent derived from melphalan, results from melphalan hydrolysis in aqueous solutions such as cell culture medium and human plasma. It enhances DNA adducts in ML-1 myeloblastic leukemia cells based on concentration and induces cytotoxicity with an IC50 value of 28.1 ?g/ml.

• Smiles:

  N(CCCl)(CCO)C1=CC=C(C[C@@H](C(O)=O)N)C=C1.Cl

• Molecular Formula:

  C13H19ClN2O3?2HCl

• Molecular Weight:

  359.68

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2707535-88-2