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22-NBD Cholesterol

CAT: 0931-T85045-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T85045-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
78949-95-8
Target
Others
Related Pathways
Others
Bioactivity
22-NBD cholesterol, a fluorescent cholesterol analog featuring a nitrobenzoxadiazole (NBD) group, serves multiple research purposes in both in vitro and in vivo settings. Its applications span the analysis of steroid uptake and esterification, the study of intracellular localization and targeting, cholesterol metabolism in mammalian and bacterial cells, and examining cholesterol intestinal absorption in hamsters. This compound showcases excitation/emission maxima at 472/540 nm when integrated into 1,2-dimyristoyl-sn-glycero-3-PC (DMPC) vesicles. Notably, the emission maximum of 22-NBD cholesterol varies with the solvent's polarity, becoming more pronounced as the polarity increases.
Smiles
C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CNC=5C=6C(C(N(=O)=O)=CC5)=NON6)C)[H])[H]
Molecular Formula
C28H38N4O4
Molecular Weight
494.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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