5α-Androstan-3β-ol

CAT: 0931-T84963-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T84963-01Size:10 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
1224-92-6
Target
Endogenous Metabolite|||Others
Related Pathways
Others|||Metabolism
Bioactivity
5?-Androstan-3?-ol, a steroidal androgen, demonstrates selective interaction with cellular components, showing affinity for the androgen receptor (AR) with an IC50 of 1.7 µM and activating the pregnane X receptor (PXR) in HepG2 cells with an EC50 of 0.8 µM. It selectively inhibits the hydroxylase activities of 16?- and 6?-hydroxylase over 16?- or 7?-hydroxylase, with IC50 values of 70 and 110 µM, compared to >150 µM for the latter enzymes, indicating a specificity in its enzyme inhibition profile. Additionally, administration of this compound at a dosage of 30 mg/kg results in a decrease in testis weight and sperm production in mice, highlighting its biological effects on male reproductive parameters.
Smiles
C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)CCC4)[H])(CC[C@]1(C[C@@H](O)CC2)[H])[H])[H]
Molecular Formula
C19H32O
Molecular Weight
276.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName
T37194-015?-Androst-16-en-3?-ol
T2962-015?-Cholestan-3?-ol
TN31115-Glutinen-3-ol
TN29003',5'-Dimethoxybiphenyl-3-ol
TCL-00258-0117β-Acetoxy-2α-bromo-5α-androstan-3-one
T131630-01Cholest-5-en-3-ol
TN11566-01Stigmast-5-en-3-ol
TYD-02619-011,5-Hexadien-3-ol
TN9654-015,6-Dimethylpyridin-3-ol
TN5066Stigmasta-5,8-dien-3-ol

Alternative Products

CatalogName
HY-W013854-015α-Androstan-3β-ol
HY-W7225565α-Androstan-3α-ol
5052765β-ANDROSTAN-3β-OL
5052775β-ANDROSTAN-3α-OL
5031435α-ANDROSTAN-3α-OL ACETATE
5031115α-ANDROSTAN-3β-OL ACETATE
5030295β-ANDROSTAN-3α-OL ACETATE
5049405α-ANDROSTAN-17β-OL
5053195α-ANDROSTAN-17α-OL
5047315α-ANDROSTAN-17β-OL-3-ONE

Popular Products