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Doripenem hydrate

CAT: 0931-T84433-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T84433-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1820954-21-9
Target
Others
Related Pathways
Others
Bioactivity
Doripenem is a broad-spectrum carbapenem antibiotic effective against both Gram-negative and Gram-positive bacteria, such as S. aureus, S. pneumoniae, E. coli, and K. pneumoniae, with minimum inhibitory concentrations (MICs) ranging from less than 0.015 to 0.3 μg/ml. It has been proven to reduce the viable bacteria count in mouse lung models of chronic P. aeruginosa respiratory tract infection at a dosage of 100 mg/kg per day. Doripenem operates by inhibiting bacterial cell wall synthesis through the formation of stable acyl-enzyme complexes with penicillin-binding proteins, leading to their inactivation. This compound has been utilized in various formulations for the treatment of bacterial infections.
Smiles
C(O)(=O)C=1N2[C@@]([C@@]([C@@H](C)O)(C2=O)[H])([C@@H](C)C1S[C@H]3C[C@@H](CNS(N)(=O)=O)NC3)[H].O
Molecular Formula
C15H24N4O6S2?XH2O
Molecular Weight
420.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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