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9-PAHSA 13C4

CAT: 0931-T84415-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T84415-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2748638-71-1
Target
Others
Related Pathways
Others
Bioactivity
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are a class of endogenous lipids whose levels are modulated by fasting and high-fat diets, and they play a role in insulin sensitivity. These compounds consist of a fatty acid—either a C-16 or C-18, such as palmitoleic, palmitic, oleic, or stearic acid—esterified to a hydroxylated C-16 or C-18 lipid. One notable FAHFA, 9-PAHSA, features an ester linkage between palmitic acid and 9-hydroxy stearic acid. PAHSAs, with 9-PAHSA being the most prevalent isomer, are significantly found in the serum and both white and brown adipose tissues of glucose-tolerant AG4OX mice, which express the Glut4 gene in adipose tissue, enhancing insulin sensitivity. Additionally, 9-PAHSA is abundant in wild type and AG4OX mice and present in humans, though at reduced levels in those with insulin resistance. 9-PAHSA is associated with improved glucose tolerance, enhanced insulin secretion, and anti-inflammatory effects in mice. The compound 19-PAHSA^13C4 represents an isotopically enriched form of this polyunsaturated fatty acid.
Smiles
C(O[13C]([13CH2][13CH2][13CH2]CCCCCCCCCCCC)=O)(CCCCCCCC(O)=O)CCCCCCCCC
Molecular Formula
C30[13C]4H66O4
Molecular Weight
542.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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