DA ZP1

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  DA ZP1 (diacetylated Zinpyr1), a highly sensitive fluorogenic Zn (II) sensor (KdZn2+= 0.6 nM), efficiently images and isolates pancreatic ?-cells and ?-like cells in vitro and purifies live stem cell-derived ?-like cells. It also enables imaging of transplanted islet grafts and endogenous mouse islets in vivo. DA ZP1 is initially non-fluorescent; however, its interaction with Zn (II) ions triggers hydrolytic cleavage of the acetyl groups, creating a robust fluorescent signal with excitation and emission maxima (?) at 490 nm and 522 nm, respectively.

• Smiles:

  CC(OC1=C(C=C2C(OC3=C(C(OC(C)=O)=C(C=C3C24OC(C5=CC=CC=C45)=O)Cl)CN(CC6=CC=CC=N6)CC7=CC=CC=N7)=C1CN(CC8=CC=CC=N8)CC9=CC=CC=N9)Cl)=O

• Molecular Formula:

  C50H40Cl2N6O7

• Molecular Weight:

  907.81

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1816254-69-9