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DA ZP1

CAT: 0931-T83928Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T83928Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1816254-69-9
Target
Others
Related Pathways
Others
Bioactivity
DA ZP1 (diacetylated Zinpyr1), a highly sensitive fluorogenic Zn (II) sensor (KdZn2+= 0.6 nM), efficiently images and isolates pancreatic β-cells and β-like cells in vitro and purifies live stem cell-derived β-like cells. It also enables imaging of transplanted islet grafts and endogenous mouse islets in vivo. DA ZP1 is initially non-fluorescent; however, its interaction with Zn (II) ions triggers hydrolytic cleavage of the acetyl groups, creating a robust fluorescent signal with excitation and emission maxima (λ) at 490 nm and 522 nm, respectively.
Smiles
CC(OC1=C(C=C2C(OC3=C(C(OC(C)=O)=C(C=C3C24OC(C5=CC=CC=C45)=O)Cl)CN(CC6=CC=CC=N6)CC7=CC=CC=N7)=C1CN(CC8=CC=CC=N8)CC9=CC=CC=N9)Cl)=O
Molecular Formula
C50H40Cl2N6O7
Molecular Weight
907.81
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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