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ACTH (6-24) (human)

CAT: 0931-T83178-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T83178-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
33512-65-1
Target
Glucocorticoid Receptor
Related Pathways
Endocrinology/Hormones
Bioactivity
Adrenocorticotropic hormone (6-24) (ACTH (6-24) (human) ) is a fragment of ACTH that acts as a competitive inhibitor of steroidogenesis prompted by full-length ACTH (1-39) and the shortened ACTH (5-24), with dissociation constants (Kd) of 13.4 nM and 3.4 nM, respectively. It also impedes the production of corticosterone and the accumulation of cyclic AMP (cAMP) triggered by human parathyroid hormone (hPTH 1-34) [1] [2].
Smiles
C([C@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H](CC2=CN=CN2)N)=O)=O)CCCNC(=N)N)=O)C(NCC(N[C@H](C(=O)N3[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N5[C@H](C(O)=O)CCC5)CC6=CC=C(O)C=C6)=O)C(C)C)=O)CCCCN)=O)[C@@H](C)C)=O)CCC4)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)=O)C(C)C)=O)CCC3)CCCCN)=O)=O)C=7C=8C(NC7)=CC=CC8
Molecular Formula
C111H175N35O21
Molecular Weight
2335.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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