Cisd2 agonist 2

• Target:

  Others|||IKZF

• Related Pathways:

  Others|||Immunology/Inflammation

• Bioactivity:

  Cisd2 agonist 2 (compound 6), with an EC50 of 191 nM, is an orally active activator of Cisd2, a protein whose levels are associated with nonalcoholic fatty liver disease (NAFLD) . In vivo studies have demonstrated that Cisd2 agonist 2 exhibits no significant toxicity in heterozygous hepatocyte-specific Cisd2 knockout (Cisd2hKO-het) mice [1].

• Smiles:

  O=C(OC)C1=C(SC(C(=O)NC2=CC=C(O)C=C2)=C1C)N

• Molecular Formula:

  C14H14N2O4S

• Molecular Weight:

  306.34

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2916371-59-8