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GluR23Y

CAT: 0931-T82295-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T82295-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
696659-27-5
Target
IGluR
Related Pathways
Membrane transporter/Ion channel, Neuroscience
Bioactivity
GluR23Y, a biologically active peptide, was utilized in an ELISA-based cell-surface assay to assess insulin-stimulated endocytosis of native AMPA receptors in cultured hippocampal neurons. GluR23Y effectively inhibited the insulin-induced decrease in receptor presence. The inhibition of insulin effects was achieved by introducing GluR23Y into neurons through fusion with the membrane transduction domain of HIV-1 TAT.
Smiles
[C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(NCC(O)=O)=O)=O)[C@H](C)C)=O)CC(N)=O)=O)NC(CNC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)N)=O)CCCCN)=O)CCC(O)=O)=O)=O
Molecular Formula
C51H69N11O16
Molecular Weight
1092.16
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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GTR19034831-01GluR23Y
CRB1001142-01TAT - GluR23Y
HY-P4106Tat-GluR23Y, scrambled
HY-P4106A-01Tat-GluR23Y, scrambled (TFA)
CRB1001142-01TAT - GluR23Y - (TAT Conjugated Peptides)

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