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H-Gly-Pro-Hyp-OH

CAT: 0931-T82200-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T82200-01Size:10 mg
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CAS Number
2239-67-0
Target
MMP
Related Pathways
Proteases/Proteasome
Purity
0.9847
Bioactivity
H-Gly-Pro-Hyp-OH is a potent and orally available anti-photoaging collagen peptide that attenuates inflammation and reduces MMP-1 and MMP-3 levels; attenuates H2O2-induced aging of dermal fibroblasts; restores cortisol-mediated inhibition of type I collagen and GR activation and (TGF) -β signaling signaling, among other things; and improves the hydration of human skin, elasticity and anti-wrinkle properties.
Smiles
C(=O)(N1[C@H](C(O)=O)C[C@@H](O)C1)[C@H]2N(C(CN)=O)CCC2
Molecular Formula
C12H19N3O5
Molecular Weight
285.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Glycyl-prolyl-hydroxyproline

Glycylprolylhydroxyproline is an oligopeptide.

CAS Number2239-67-0
PubChem CID11778669
IUPAC Name(2S,4R)-1-[(2S)-1-(2-aminoacetyl)pyrrolidine-2-carbonyl]-4-hydroxypyrrolidine-2-carboxylic acid
Molecular FormulaC12H19N3O5
Molecular Weight285.30
XLogP-4.3
Topological Polar Surface Area124
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Heavy Atom Count20
Formal Charge0
Complexity427
SMILES
C1C[C@H](N(C1)C(=O)CN)C(=O)N2C[C@@H](C[C@H]2C(=O)O)O
InChI
InChI=1S/C12H19N3O5/c13-5-10(17)14-3-1-2-8(14)11(18)15-6-7(16)4-9(15)12(19)20/h7-9,16H,1-6,13H2,(H,19,20)/t7-,8+,9+/m1/s1
InChIKey
SZEOBSAZWJLOGY-VGMNWLOBSA-N
Chemical Structure
2D Structure
2D structure of Glycyl-prolyl-hydroxyproline
CAS: 2239-67-0
CID: 11778669
Formula: C12H19N3O5
MW: 285.30
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight285.30
XLogP3-4.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass285.13247072
Monoisotopic Mass285.13247072
Topological Polar Surface Area124 Ų
Heavy Atom Count20
Formal Charge0
Complexity427
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes