Products for Research Use Only

PNMT-IN-1

CAT: 0931-T81432-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T81432-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Adrenergic Receptor, Others
Related Pathways
Neuroscience, GPCR/G Protein, Others
Bioactivity
PNMT-IN-1 (inhibitor 4) is a selective second generation inhibitor [1] of phenylethanolamine N-methyltransferase (PNMT), exhibiting a Ki value of 1.2 nM and an IC50 value of 81 nM. Additionally, it disrupts the activity of DNMT1 and DNMT3b, with IC50 values of 61 μM and 17 μM, respectively, and antagonizes the action of epinephrine.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C