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PZ-1922

CAT: 0931-T81335-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T81335-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
5-HT Receptor, Monoamine Oxidase
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
PZ-1922 (Compound 16), able to cross the blood-brain barrier, is a dual antagonist for 5-HT6R and 5-HT3R with K i values of 17 nM and 0.45 nM, respectively. It also reversibly inhibits MAO-B with a pIC50 of 8.93. Moreover, PZ-1922 mitigates scopolamine (SCOP) -induced memory deficits in rats as observed in the novel object recognition (NOR) test and hinders Aβ-induced memory impairment in the T-maze test [1].
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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